The Importance of Small Airways Disease in Asthma

Small airways disease is highly prevalent in patients with asthma, even in those with mild symptoms. One of the key characteristics of small airways disease is airway remodelling, with the loss of alveolar attachment.

Given the challenges with assessment, further studies were required to better understand how small airways disease contributes to the clinical impact of asthma. The ATLANTIS study¹ was therefore designed to identify the combination of physiological testing that best characterises the presence and extent of small airways disease.

This webinar Dr Salman Siddiqui presents the data from the ATLANTIS study, exploring the results of the various diagnostic tools available on detecting small airways disease in asthmatic patients.

References

1. Postma- DS, et al. Lancet Respir Med 2019; doi: 10.1016/S2213-2600(19)30049-9.

We hope that you found the content valuable. To ensure that we continue to provide topics and content of interest, we would very much value your feedback by completing a short questionnaire.

• Professor Salman Siddiqui

  Professor of Airway Disease and Respiratory Medicine, Adult Severe Asthma Lead and Translational Lead for Breathomics

  Read biography
  Professor Salman Siddiqui

  Professor of Airway Disease and Respiratory Medicine, Adult Severe Asthma Lead and Translational Lead for Breathomics Leicester University & Glenfield Hospital

  Role and Location 

  Professor Siddiqui was Professor of Airway Disease and Respiratory Medicine at Leicester University and NIHR Respiratory Biomedical Research Unit, Glenfield Hospital. He led he adult severe asthma service at Glenfield Hospital which was one of the largest severe asthma services in the UK and Europe. Professor Siddiqui leads the respiratory Biomedical Research Centre (BRC) theme for phenotyping and biomarkers of airway diseases and was the translational lead for the East Midlands Breathomics (EMBER) MRC molecular pathology node.

  Education 

  Professor Siddiqui achieved his BM in Medicine at the University of Southampton in 2000 and his PhD in Respiratory Sciences in 2008.

  Research Interests

  Professor Siddiqui has specific clinical interests in severe asthma, phenotyping and biomarkers of airway diseases. He also has interests in experimental medicine in severe asthma/COPD and advanced healthcare technologies.