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  • Respiratory

The Importance of Small Airways Disease in Asthma

Small airways disease is highly prevalent in patients with asthma, even in those with mild symptoms. One of the key characteristics of small airways disease is airway remodelling, with the loss of alveolar attachment.

Given the challenges with assessment, further studies were required to better understand how small airways disease contributes to the clinical impact of asthma. The ATLANTIS study1 was therefore designed to identify the combination of physiological testing that best characterises the presence and extent of small airways disease.

This webinar Dr Salman Siddiqui presents the data from the ATLANTIS study, exploring the results of the various diagnostic tools available on detecting small airways disease in asthmatic patients.


1. Postma- DS, et al. Lancet Respir Med 2019; doi: 10.1016/S2213-2600(19)30049-9.

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Professor Salman Siddiqui

Professor Siddiqui is professor of Airway Disease and Respiratory Medicine at Leicester University and NIHR Respiratory Biomedical Research Unit, Glenfield Hospital. He leads the adult severe asthma service at Glenfield Hospital which is one of the largest severe asthma services in the UK and Europe. Professor Siddiqui leads the respiratory Biomedical Research Centre (BRC) theme for phenotyping and biomarkers of airway diseases and is the translational lead for the East Midlands Breathomics (EMBER) MRC molecular pathology node.