Bullet flag-united-kingdom flag-ireland


  • Respiratory

Perceptions and Challenges to Adherence in Asthma

Medication non-adherence has been suboptimal for decades and ranges from 30-50%.1 Poor medication adherence is recognized as one of the main reasons for suboptimal asthma management and poor clinical outcomes.2 Underuse of maintenance ICS may increase the risk of exacerbations because the underlying inflammation is not addressed.3,4

Healthcare professionals must explore patients’ perspectives of medicines and the reasons why they may not want or are unable to use them. Healthcare professionals have a duty to help patients make informed decisions about treatment and use appropriately prescribed medicines to best effect.1

Within this webinar, Dr Anna Murphy discusses medicine adherence in respiratory, and the importance of exploring the patient specific barriers to achieve good adherence. She then highlights ways in which to address these barriers with approaches such as personalised care, shared decision making and health coaching.


1. NICE guidelines. Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence. January 2009. Available at: https://www.nice.org.uk/Guidance/CG76 [Last accessed November 2021].

2. Gamble J et al. The prevalence of nonadherence in difficult asthma. Am J Respir Crit Care Med. 2009 Nov 1; 180(9): 817-22.

3. Engelkes M et al. Medication adherence and the risk of severe asthma exacerbations: a systematic review. Eur Respir J. 2015 Feb; 45(2): 396-407.

4. Williams LK, et al. Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence.J Allergy Clin Immunol. 2011 Dec; 128(6): 1185-1191.e2.

We hope that you found the content valuable. To ensure that we continue to provide topics and content of interest, we would very much value your feedback by completing a short questionnaire.

Dr Anna Murphy

Dr Murphy is a consultant respiratory pharmacist at University Hospitals of Leicester NHS Trust and honorary visiting professor at DeMontfort University. The clinical aspect of her post offers assessment, medicines optimisation, monitoring and advice to people with respiratory disease, working both in hospital and across the interface. Research interests include medicine adherence in people with respiratory disease and pharmacy practice research. Dr Murphy has published widely and produced the “7-Steps to Success” education materials. She currently works with several national groups and organisations on issues surrounding prescribing in respiratory disease.